中文名称:c(RGD)环肽:c(RGDyC)
英文名:cyclo(RGDyC)
单字母:cyclo(RGD-DTyr-C)(main chain cyclo)
三字母:cyclo(Arg-Gly-Asp-DTyr-Cys)(main chain cyclo)
分子式:C24H34N8O8S1
分子量:594.64
作用:c(RGDyC)是一种由5个氨基酸组成的首尾酰胺环肿瘤靶向肽,它通过与细胞表面的 αvβ3 整合素结合,特异性靶向肿瘤微血管和癌细胞。被用于脂质体研究,用于胶质母细胞瘤中肿瘤血管系统和癌细胞的双重靶向,一项体外硼中子俘获疗法研究。
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