当然可以！以下是一个简单的Python小游戏示例：猜拳游戏。在这个游戏中，玩家将与计算机进行猜拳（石头、剪刀、布）。

import random

def get_computer_choice():
    choices = ['石头', '剪刀', '布']
    return random.choice(choices)

def get_player_choice():
    choice = input("请输入你的选择（石头、剪刀、布）：")
    while choice not in ['石头', '剪刀', '布']:
        choice = input("输入无效，请重新输入你的选择（石头、剪刀、布）：")
    return choice

def determine_winner(player_choice, computer_choice):
    if player_choice == computer_choice:
        return "平局！"
    elif (player_choice == "石头" and computer_choice == "剪刀") or \
         (player_choice == "剪刀" and computer_choice == "布") or \
         (player_choice == "布" and computer_choice == "石头"):
        return "你赢了！"
    else:
        return "你输了！"

def play_game():
    player_choice = get_player_choice()
    computer_choice = get_computer_choice()
    print(f"\n你的选择是：{player_choice}")
    print(f"计算机的选择是：{computer_choice}")
    result = determine_winner(player_choice, computer_choice)
    print(result)

if __name__ == "__main__":
    play_game()

在这个游戏中，玩家输入他们的选择（石头、剪刀或布），计算机随机生成一个选择，然后程序会判断并宣布赢家。你可以运行这段代码，并根据提示来玩猜拳游戏。